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dc.contributor.authorSalem, Gamal A
dc.contributor.authorMurad, Suzan k
dc.contributor.authorAlamyel, Fathi B
dc.contributor.authorEbowah, Manal A
dc.contributor.authorMahmoud, Marwa A
dc.contributor.authorAbulifa, Abdullah R
dc.date.accessioned2018-10-02T10:30:19Z
dc.date.available2018-10-02T10:30:19Z
dc.date.issued2018-12
dc.identifier.urihttp://mdr.misuratau.edu.ly/handle/123456789/753
dc.description.abstractThe spread of resistant Enterobacteriaceae to antibiotics in chicken farms constitute a reservoir of resistant genes that could be easily transmitted to contact human. So, this study conducted to investigate the prevalence of ciprofloxacin and gentamycin resistance profiles and the frequency of aac (6')-Ib gene in chicken farms in Misurata city and living population in the vicinity of these farms. (135) cloacae swab from chicken and (107) urine samples from human living in these farms were collected. Isolation and identification of different Enterobacteriaceae strains is performed in antibiotic resistance profiles against ciprofloxacin and gentamycin antibiotics. DNA extracted from each sample and further screening for aac (6')-Ib-cr in ciprofloxacin and/or gentamycin resistant isolates by using of using PCR technique. Our results showed that 88.8% and 93.4% of chicken and human isolates confirmed to be Enterobacteriaceae respectively. There were non-significant association between the source of Enterobacteriaceae isolates and quinolones or aminoglycosides resistance profiles. The screening of the genetic determinant of gentamycin and ciprofloxacin resistance aac (6')-Ib-cr, revealed an impressive proximity between the frequency of this gene within the chicken and human isolates (33.6%, 33 %) respectively. In conclusion quinolones and aminoglycosides resistance profiles and the frequency of aac (6')-Ib-cr between chicken and human were nearly comparable, that would suggest the possible transmission of this gene from chicken to human.en
dc.language.isoenen
dc.publisherمجلة العلوم الطبيةen
dc.subjectAntibiotic resistanceen
dc.subjectQuinolonesen
dc.subjectAminoglycosidesen
dc.subjectEnterobacteriaceaeen
dc.titleSTUDYING THE PREVALENCE OF QUINOLONES AND AMINOGLYCOSIDES RESISTANCE PROFILES AND TRANSMISSION OF AAC (6')-IB GENE FROM CHICKEN TO CONTACT HUMANen
dc.typeArticleen


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